IPAMORELIN
Selective pentapeptide growth-hormone secretagogue and ghrelin-receptor agonist.
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For laboratory research use only. Not for human or veterinary consumption, diagnostic or therapeutic use. Handle in accordance with institutional safety procedures.
Product Overview
Scientific profile
IPAMORELIN is a synthetic pentapeptide growth-hormone secretagogue that acts as an agonist of the ghrelin receptor (GHS-R1a). It was described by Raun et al. (European Journal of Endocrinology, 1998) as the first GH secretagogue with a selectivity profile comparable to GHRH.
Research Background
In animal studies IPAMORELIN produced dose-dependent GH release without significant elevation of ACTH or cortisol, distinguishing it from earlier GH-releasing peptides such as GHRP-6 and GHRP-2. The incorporation of α-aminoisobutyric acid (Aib), D-2-naphthylalanine and D-phenylalanine confers receptor potency and proteolytic stability.
Areas of Investigation
- GHS-R1a pharmacology and ghrelin-mimetic signalling
- Pulsatile GH release and somatotroph physiology
- Selectivity of GH secretagogues versus ACTH/cortisol release
- Synergy studies with GHRH analogues
Analytical Profile
C-terminally amidated. Purity by reverse-phase HPLC; identity confirmed by ESI-MS. Supplied as a lyophilized peptide.
Specifications
Chemical & physical data
CAS Number
170851-70-4
Molecular Formula
C38H49N9O5
Molecular Weight
711.85 g/mol
Physical Form
Lyophilized Powder
Storage Guidelines
-20°C, desiccated and protected from light
Amino Acid Sequence
H-Aib-His-D-2Nal-D-Phe-Lys-NH2
Quality Assurance
Every vial. Every batch. Documented.
Our release process is built for research reproducibility — independent analytics, traceable batches and tamper-evident authentication.
>99% Purity Guaranteed
Every batch must exceed 99% purity by reverse-phase HPLC before it is released to the catalog.
3rd Party Laboratory Tested
Independent analytical labs confirm purity by HPLC and molecular identity by mass spectrometry (MS).
Batch-Tracked Serialization
Each box carries a unique 6-character code linked to its production batch and verifiable online.
Strict Research-Grade Synthesis
Solid-phase synthesis, lyophilization and sealed vialing under controlled, documented conditions.
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