SELANK
Synthetic tuftsin analogue (Thr-Lys-Pro-Arg-Pro-Gly-Pro) studied in neuro-immune research.
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For laboratory research use only. Not for human or veterinary consumption, diagnostic or therapeutic use. Handle in accordance with institutional safety procedures.
Product Overview
Scientific profile
SELANK is a synthetic heptapeptide in which the immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg) is extended with the stabilising Pro-Gly-Pro sequence. Like SEMAX, it was developed at the Institute of Molecular Genetics, Russian Academy of Sciences.
Research Background
Rodent studies have reported anxiolytic-like behavioural effects, and mechanistic work has examined allosteric modulation of GABA-A receptor signalling, inhibition of enkephalin-degrading enzymes and changes in the expression of cytokines such as IL-6. The peptide is therefore studied at the interface of neuroscience and immunology.
Areas of Investigation
- GABAergic signalling and behavioural pharmacology models
- Enkephalinase activity and endogenous opioid-peptide stability
- Cytokine expression and neuro-immune interaction
- Tuftsin-derived peptide structure–activity relationships
Analytical Profile
Purity by reverse-phase HPLC; identity confirmed by ESI-MS. Supplied as a lyophilized peptide.
Specifications
Chemical & physical data
CAS Number
129954-34-3
Molecular Formula
C33H57N11O9
Molecular Weight
751.87 g/mol
Physical Form
Lyophilized Powder
Storage Guidelines
-20°C, desiccated and protected from light
Amino Acid Sequence
H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH
Quality Assurance
Every vial. Every batch. Documented.
Our release process is built for research reproducibility — independent analytics, traceable batches and tamper-evident authentication.
>99% Purity Guaranteed
Every batch must exceed 99% purity by reverse-phase HPLC before it is released to the catalog.
3rd Party Laboratory Tested
Independent analytical labs confirm purity by HPLC and molecular identity by mass spectrometry (MS).
Batch-Tracked Serialization
Each box carries a unique 6-character code linked to its production batch and verifiable online.
Strict Research-Grade Synthesis
Solid-phase synthesis, lyophilization and sealed vialing under controlled, documented conditions.
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